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These are really promising initial signs, but it's important to remember the long-term side effects are still coming to light.that novel weight loss drugs – known as glucagon-like peptide-1 receptor agonists – could be causing significant skeletal muscle loss as well as fat loss. But there's not enough data to say for sure.
For 21 days, researchers at Alberta administered semaglutide – the active ingredient in Ozempic – to both lean and obese mice withoutThe obese mice lost about 30 percent of their body weight and 65 percent of their fat mass compared to untreated mice. To explore further, the team of researchers, led by clinical scientist Matthew Martens, turned to human cells. In the lab, when human cardiac muscle cells were treated with semaglutide, they showed significant reductions in size.
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