A new study shows that multidrug-resistant tuberculosis (TB) strains resistant to new drugs can be transmitted between patients. This finding highlights the urgent need for new treatments and preventative measures to combat this growing threat.
Bacteria that are resistant to antibiotics are one of the top 10 global health threat s, according to the World Health Organization. Therefore, researchers are looking for new antibiotics to counter this problem. Findings in animal models show that a US Food and Drug Administration (FDA)-approved antibiotic regimen for multidrug-resistant (MDR) tuberculosis (TB) may not work for TB strains that are resistant to new drugs.
The study found that these resistant strains can be transmitted between patients. Multidrug resistance (MDR) -- a process in which tumors become resistant to multiple medicines -- is the main cause of failure of cancer chemotherapy. Tumor cells often acquire MDR by boosting their drug efflux pumps, increasing their DNA repair capacity, or altering their target site. A new drug regimen for multidrug-resistant tuberculosis shows early effectiveness in 85 percent of patients in a cohort including many with serious comorbidities. The results suggest a global need for access to effective treatment options for MDR-TB
Tuberculosis Drug Resistance Transmission Antibiotics Health Threat
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