Dopamine--why you shouldn't mess with it.
" and you will learn that its nicknames are the "happy hormone" and the "pleasure molecule" and that it is among the most important chemicals in our brains. With The Guardian branding it "the Kim Kardashian of neurotransmitters," dopamine has become a true pop-science darling — people across the globe have attempted to boost their mood with dopamine fasts and dopamine dressing.
Around the same time, several scientists across Europe successfully synthesized dopamine, but those discoveries were shelved without much fanfare. For the next three decades, dopamine and levodopa were pushed into academic obscurity. Just before World War II, a group of German scientists showed that levodopa is metabolized to dopamine in the body, while another German researcher, Hermann Blaschko, discovered that dopamine is an intermediary in the synthesis of noradrenaline.
in guinea pigs, proving that dopamine indeed had physiologic activity that was independent of other catecholamines.While Blaschko and Hornykiewicz were puzzling over dopamine's physiologic role in the body, across the ocean at the NationalInstitute in Maryland, pharmacologist Bernard Brodie and colleagues were laying the groundwork for the discovery of dopamine's starring role in the brain.
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