Do system-level DOAC therapy management services affect anticoagulation outcomes for AF patients compared to usual care? JAMANetworkOpen DOAC therapy anticoagulation AF patients
By Pooja Toshniwal PahariaJul 10 2023Reviewed by Lily Ramsey, LLM In a recent study published in JAMA Network Open, researchers compared outcomes related to three direct oral anticoagulant care models to prevent anticoagulation-associated adverse effects among adult atrial fibrillation patients.
About the study In the present retrospective cohort pharmacoepidemiologic study, researchers investigated whether system-level DOAC treatment management services could improve anticoagulation-associated outcomes among patients initiating direct oral anticoagulants under different models for DOAC care.
The anticoagulation management services cohort comprised individuals prescribed a DOAC and proactively enrolled in the AMS led by the pharmacist managing warfarin treatment. The study participants were followed until a study outcome occurred , termination of Kaiser Permanente membership, or 31 December 2020.
Over two years of follow-up , AF outcomes in the usual care and PMT or pharmacist-managed anticoagulation management service care models did not differ significantly from usual care recipients.
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