Science, Space and Technology News 2024
MIT researchers have determined that the DIANA MRI method, initially claimed to detect direct neural activity, actually produces signals from its imaging process, not from brain activity. Experiments showed that these signals were artifacts of the imaging system’s setup, challenging the method’s efficacy and raising concerns about its reliability in neuroscientific research. Credit: SciTechDaily.
The method, first described in 2022, generated excitement within the neuroscience community as a potentially transformative approach. However, a study from the lab of MIT Professor Alan Jasanoff, reported in the journal, demonstrates that MRI signals produced by the new method are generated in large part by the imaging process itself, not neuronal activity.
Recreating the MRI procedure reported by DIANA’s developers, postdoc Valerie Doan Phi Van imaged the brain of a rat as an electric stimulus was delivered to one paw. Phi Van says she was excited to see an MRI signal appear in the brain’s sensory cortex, exactly when and where neurons were expected to respond to the sensation on the paw. “I was able to reproduce it,” she says. “I could see the signal.
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