A substantial proportion of patients with psoriasis, uveitis, or colitis and undiagnosed chronic back pain had axial spondyloarthritis, a study involving two multicenter cohorts showed.
Patients with psoriasis, uveitis, or colitis who present with undiagnosed chronic back pain should be referred to a rheumatologist for the assessment of axial spondyloarthritis , with MRI being a more accurate diagnostic method than clinical features.Researchers assessed the prevalence of axSpA according to the extra-articular presentation and human leukocyte antigen B27 status in two Canadian cohorts .
Participants were referred to rheumatologists with expertise in axSpA for structured diagnostic evaluations, including history, physical exam, levels of C-reactive protein, HLA-B27 status, and imaging studies. The primary outcome was the proportion of patients diagnosed with axSpA after final global evaluation, and the secondary outcome was the impact of MRI on diagnosis and classification.AxSpA diagnoses were made in 46.7% with psoriasis, 61.6% with uveitis, and 46.8% with colitis in the SASPIC-1 cohort and in 23.5%, 57.9%, and 23.3%, respectively, in the SASPIC-2 cohort.
Musculoskeletal clinical features were not helpful in differentiating between patients with and without axSpA.
Axspa Ankylosing Spondylitis Rheumatoid Spondylitis Rheumatoid Arthritis Of The Spine Bechterew's Disease Bechterew Syndrome Marie Strumpell Disease Marie Struempell Disease Spondyloarthritis Spondylosis Back Pain Colitis Pain Pain Management Chronic Back Pain Chronic Pain Of The Back Uveitis Inflammatory Bowel Disease IBD - Inflammatory Bowel Disease IBD
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