The risk for uterine fibroids in midlife women seemed to decrease in those receiving diabetes treatment but varied based on menopausal status.
Diabetes is associated with a lower incidence of uterine fibroids in midlife women receiving diabetes treatment, especially metformin. The association between diabetes and the risk for uterine fibroids may vary based on menopausal status.Previous studies have provided inconsistent evidence regarding associations between the risk for uterine fibroids and markers of cardiometabolic health, such as fasting insulin, fasting glucose, and diabetes.
They included participants from the Study of Women's Health Across the Nation cohort who reported fibroid diagnoses at enrollment and during 13 follow-up visits. Discrete-time survival models were used to estimate the hazard ratios for the associations of biomarkers and diabetes with fibroid diagnoses, adjusted for demographics and healthcare utilization.Researchers identified 2570 eligible women , among whom approximately 3% had diabetes at baseline.This association was particularly strong among participants with treated diabetes, especially those on metformin, who had a 51% lower incidence of self-reported fibroids than those without diabetes.
Uterine Fibroids Fibroma Fibroid Fibroid Tumor Uterine Womb Biomarker Biological Marker Multi-Biomarker Disease Activity MBDA Multibiomarker Disease Activity Blood Healthcare And Medical Technology Health And Medical Tech Health And Med Tech Health And Medical Technology Healthcare Technology Medical Technology Practice Management Revenue
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