You've got to admit it's a looker
but no less intriguing) to name but a few. Devialet Mania in sandstorm is also a looker, no?
It's a looker isn't it? Aside from the new colorways, it remains a futuristic eyeball-shaped wireless speaker with a delightful little handle at the top and push-push bass radiators like irises on either side. And at 2.3kg it's reassuringly heavy, almost like a kettlebell, but far more beautiful. ASC and SAM are the two technologies you need to understand. The former uses four mics and embedded calibration tech to allow the speaker to automatically adapt the audio rendering to suit its surroundings. No wafting your phone around the room, no space-war sounds for several minutes, it just does its thing in a matter of seconds.
The latter involves four full-range drivers in the top portion of the speaker and those two SAM-powered subwoofers in a push-push configuration, to promise true omnidirectional stereo sound from 30Hz to 20kHz. During my time with it in November last year, it sounded an awful lot larger, fuller and just better than any of the
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Retinal microvascular changes in diabetic patients with diabetic nephropathy - BMC Endocrine DisordersBackground To explore the characteristics of retina microvascular changes in patients with diabetic nephropathy (DN) and its risk factors. Methods Retrospective, observational study. 145 patients with type 2 diabetic mellitus (DM) and DN were included in the study. Demographic and clinical parameters were obtained from medical records. Presence of diabetic retinopathy (DR), hard exudates (HEs) and diabetic macular edema (DME) were evaluated according to the color fundus images, optical coherence tomography (OCT) and fluorescence angiography (FFA). Results DR accounted for 61.4% in type 2 DM patients with DN, of which proliferative diabetic retinopathy (PDR) accounted for 23.6% and sight threatening DR accounted for 35.7%. DR group had significantly higher levels of low-density lipoprotein cholesterol (LDL-C) (p = 0.004), HbA1c (P = 0.037), Urine albumin creatine ratio (ACR) (p | 0.001) and lower level of estimated glomerular filtration rate (eGFR) (P = 0.013). Logistic regression analysis showed DR was significantly associated with ACR stage (p = 0.011). Subjects with ACR stage3 had higher incidence of DR compared with subjects with ACR stage1 (OR = 24.15, 95%CI: 2.06–282.95). 138 eyes of 138 patients were analyzed for HEs and DME, of which 23.2% had HEs in posterior pole and 9.4% had DME. Visual acuity was worse in HEs group than in non-HEs group. There was significant difference in the LDL-C cholesterol level, total cholesterol (CHOL) level and ACR between HEs group and non-HEs group. Conclusions A relatively higher prevalence of DR was found in type 2 DM patients with DN. ACR stage could be recognized as a risk factor for DR in DN patients. Patients with DN needs ophthalmic examination more timely and more frequently.
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