Scientists find more evidence that breastmilk of those vaccinated against COVID-19 may protect infants
To protect against SARS-CoV-2 infection, the immune system must mount a robust and specific response. In addition to SARS-CoV-2-specific antibody concentration, antibody specificity, affinity, and neutralizing capacity are also necessary to elicit a proper immune response. As such, we hypothesize that there is a transfer of neutralizing HM SARS-CoV-2 specific IgA and IgG to the intestinal tract of breast-fed infants that can protect them from COVID-19 infection.
Participants completed a questionnaire collecting maternal/infant demographics, medical and family history, and vaccination side effects upon agreeing to participate.Maternal blood samples were collected via venipuncture or finger prick in ethylenediaminetetraacetic acid-coated tubes at the designated time points. Plasma was separated from cellular matter by centrifugation at 2000 ×For milk, mothers were instructed to express samples of 10–30 ml.
To determine the neutralization capability of SARS-CoV-2 antibodies, we used an assay containing vesicular stomatitis virus expressing the SARS-CoV-2 Wuhan-hu-1 wild type strain spike protein and green fluorescent protein described in a previously published study []. Milk, plasma, or stool samples were mixed with VSV and later incubated with baby hamster kidney cells expressing human ACE2 receptors. GFP frequency was measured by flow cytometry to quantify BHK-ACE2 cell infectivity.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Study explores incidence, severity, and long COVID associations of SARS-CoV-2 reinfectionsResearchers used electronic health records to characterize the incidence, biomarkers, attributes, and severity of SARS-CoV-2 reinfections and evaluated the association between reinfections and long coronavirus disease (COVID).
Read more »
Study shows booster vaccinations against SARS-CoV-2 effective but protection wanes rapidlyA recent study posted to medRxiv* assessed the effectiveness of primary and booster vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Netherlands.
Read more »
Bivalent boosters tested against all SARS-CoV-2 Omicron lineagesIn a recent study posted to the bioRxiv* preprint server, researchers in the United States assessed the impact of the bivalent messenger ribonucleic acid (mRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine on the antibody-mediated neutralization of the SARS-CoV-2 Omicron lineages.
Read more »
The protective effect of previous infections and vaccinations on SARS-CoV-2 Omicron infectionThe protective effect of previous infections and vaccinations on SARS-CoV-2 Omicron infection medrxivpreprint UniUtrecht radboudumc covid coronavirus covid Omicron infection vaccination
Read more »
Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjectsReal-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects covid coronavirus covid hospital vaccine vaccination
Read more »
Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bondsResearchers discovered that the spike protein of SARS-CoV-2 is susceptible to cleavage at the disulfide bonds, and the vulnerability to reductive cleavage varies across variants, with the Omicron variant family being highly susceptible to reduction.
Read more »