Researchers at the University of Helsinki have demonstrated that certain strains of Desulfovibrio bacteria are the likely cause of Parkinson’s disease in most cases. The study enables the screening of the carriers of Desulfovibrio strains and the removal of the bacteria from the gut – also making it
Only a small share, or roughly 10%, of Parkinson’s disease is caused by individual genes,” says Professor Per Saris from the University of Helsinki.DesulfovibrioAggregation of alpha-synuclein in a nerve cell. Credit: Timo Myöhänen research group
The principal finding of the group’s recently published study was that these strains in patients with Parkinson’s disease cause aggregation of the α-synuclein protein on a statistically significant level in a model organism for Parkinson’s disease. The wormstrains isolated from healthy individuals do not cause α-synuclein aggregation to the same degree. In contrast, the aggregates caused by the“Our findings make it possible to screen for the carriers of these harmfulbacteria.
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