A research group have used whole-genome sequencing to unravel the complex ancestry of the Japanese population. The analysis supports an earlier study that proposed that the Japanese population originated from admixtures of three ancestral groups, challenging the long-held dual-structure model.
A research group led by scientists from the RIKEN Center for Integrative Medical Sciences in Japan have used whole-genome sequencing to unravel the complex ancestry of the Japanese population. The analysis supports an earlier study that proposed that the Japanese population originated from admixtures of three ancestral groups, challenging the long-held dual-structure model, and also provides new evidence of Neanderthal and Denisovan influences in the population.
To see whether these findings could provide insights into clinically relevant genetic variants, they examined two well-known pathogenic variants associated with hereditary breast cancer. The first, a variant of thegene, is only found in Japanese populations, and is more common in the east than the west of the country. This implied that it arose in Japanese people with Northeast Asian ancestry and then spread westward.
According to Chikashi Terao, leader of the research group,"Though our findings were interesting because of the new insights they have given us into the origins of the Japanese people, we also believe that our work will serve as a reference for future genetic research beyond the Japanese population, as it could be used in areas such as personalized medicine.
Genes Gene Therapy Human Biology Social Issues Racial Disparity STEM Education Public Health
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
How a new class of Japanese stars is changing baseballJapanese stars help shape MLB. Now MLB helps shape Japanese baseball, too.
Read more »
Decoding Success: The Power And Potential Of People AnalyticsFounder and CEO of Valuematrix.ai. A Nasscom Deeptech and CII Mentor who's associated with many startups in the AI and SaaS space. Read Aditya Malik's full executive profile here.
Read more »
Forex fundamentals unpacked: Decoding the drivers of major currency movementsThis report looks at the recent performance and future outlook for the major currencies, including the US Dollar, Euro, British Pound, Japanese Yen, Swiss Franc, and Canadian Dollar.
Read more »
Decoding development: mRNA's role in embryo formationA new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights into how pluripotent cells adopt specialized identities through gene expression.
Read more »
Decoding health insurance: your casual guide to finding the perfect planAlright, folks, buckle up because we’re diving into the realm of health insurance plans, and we’re keeping it as chill as your favorite coffee shop playlist. There are four main players in this game, and today, we’re spotlighting the one that goes by many names—Individual and Family Plans, also known as Obamacare, Marketplace, ACA, or Exchange.
Read more »
Life's insiders: Decoding endosymbiosis with mathematicsEndosymbiosis, the intimate and long-term relationship where one organism lives inside another, is a cornerstone of life as we know it, and a key to the emergence of complex life on Earth. Many of the mysteries surrounding endosymbiosis are difficult to tackle using empirical approaches alone.
Read more »