Two molecular languages at the origin of life have been successfully recreated and mathematically validated, thanks to pioneering work by Canadian scientists at Université de Montréal.
Journal of the American Chemical Society
In yeasts, for example, upon detecting and binding a mating pheromone, billions of molecules will communicate and coordinate their activities to initiate union, said Vallée-Bélisle, holder of a Canada Research Chair in Bioengineering and Bionanotechnology. Although these two languages are observed in all molecular systems of all living organisms, it is only recently that scientists have started to understand their rules and principles—and so use these languages to design and program novel artificial nanotechnologies.
To do so, his doctoral student Dominic Lauzon, first author of the study, had the idea of creating a DNA-based molecular system that could function using both languages."DNA is like Lego bricks for nanoengineers," said Lauzon."It's a remarkable molecule that offers simple, programmable and easy-to-use chemistry.
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