The dietary supplement D-mannose performed similarly to a placebo among women with recurrent urinary tract infections.
A natural sugar used to treat recurring urinary tract infections did not reduce future episodes, outpatient visits, the use of antibiotics, or symptoms compared with a placebo, according to a new study.D-Mannose is recommended as a natural alternative to antibiotics and sold as a dietary supplement; research showing the efficacy of
The double-blind, randomized controlled trial followed 598 women older than 18 years with a history of rUTIs over 6 months from nearly 100 primary care clinics in the United Kingdom. Patients took 2 g of D-mannose or placebo powder daily and recorded their symptoms using a daily diary or through responses to health surveys, weekly questionnaires, and phone calls.Approximately 51% of participants who took D-mannose and 55.7% of those who took a placebo contacted a healthcare professional reporting a UTI School for Primary Care Research and the NIHR Oxford Biomedical Research Centre.
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