Two different doses of crisugabalin resulted in significantly greater pain reductions in adults with postherpetic neuralgia than placebo in a phase 3 trial.
Crisugabalin — an oral calcium channel alpha 2 delta-1 subunit ligand — was safe and well-tolerated at doses of 40 mg/d and 80 mg/d and significantly reduced pain scores in patients withinvolving 366 patients in China with PHN with an average daily pain score ≥ 4 on the numeric pain rating scale who were randomly assigned to receive either crisugabalin 40 mg/d , 80 mg/d , or placebo for 12 weeks.
Patients who did not experience any serious toxic effects in these 12 weeks entered a 14-week open-label extension phase and received crisugabalin 40 mg twice daily.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Pain Herpes Zoster Shingles Postherpetic Neuralgia Neuralgia Depression Cyclic Antidepressant Tricyclic Antidepressant Tricyclics TCA - Tricyclic Antidepressant Healthcare And Medical Technology Health And Medical Tech Health And Med Tech Health And Medical Technology Healthcare Technology Medical Technology Patient Safety Adverse Effects Side Effects Antidepressant
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
First doses of mpox vaccine from the United States arrive in CongoAuthorities in Congo say 50,000 doses of the mpox vaccine from the United States have arrived in the country. The arrival on Tuesday came a week after the first batch arrived from the European Union. Around 250,000 doses overall have arrived in Congo so far.
Read more »
First doses of mpox vaccine from the United States arrive in CongoAuthorities in Congo say 50,000 doses of the mpox vaccine from the United States have arrived in the country.
Read more »
First doses of mpox vaccine from the United States arrive in CongoAuthorities in Congo say 50,000 doses of the mpox vaccine from the United States have arrived in the country.
Read more »
First doses of mpox vaccine from the United States arrive in CongoAuthorities in Congo say 50,000 doses of the mpox vaccine from the United States have arrived in the country.
Read more »
Congo Receives First Doses of Mpox Vaccine From US50,000 doses of the mpox vaccine arrived in Congo from the United States as vaccinations are expected to begin on October 2.
Read more »
First Doses of Mpox Vaccine Reach Africa, But Many More Are NeededAs mpox continues to spread in Africa, Congolese authorities said Thursday that the first batch of vaccines have arrived in that country's capital.
Read more »