CRISPR changes are now fully reversible, and the world will never be the same.
The gene-editing system CRISPR-Cas9 which has revolutionized genetic engineering over the past decade involves cutting DNA strands which is a process that can be quite hard to control and can result in unwanted genetic changes.
The researchers created a tiny protein machine to build an epigenetic editor that could imitate natural DNA methylation, which is an epigenetic mechanism that occurs by the addition of a methyl group to DNA. The machine, guided by small RNAs, can turn methyl groups onto specific spots on the strand. The methylated genes are then"silenced," or turned off, which is where the name of the machine comes from.
We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more: