COVID vaccines might stop a '4th wave' in the U.S. But the rest of the world isn't so lucky.

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COVID vaccines might stop a '4th wave' in the U.S. But the rest of the world isn't so lucky.
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Despite the rosy view from a few select countries, the total number of COVID-19 cases worldwide is rising. After peaking on Jan. 11 and dropping by half over the next month, global cases reversed course in mid-February and began to rebound.

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This is consistent with a reanalysis of the phase 3 clinical trial data reported in 2020 in the New England Journal of Medicine. In that study, the 52% protection from the first dose included infections that occurred in the first 10 days after vaccination, when one would not expect the vaccine to have had time to generate protective anti-spike antibodies.

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