Americans could have different immune responses to the latest COVID-19 vaccines this fall based on how they first experienced the coronavirus.
and boosters, as well as prior infections, have created different layers of immunity in cities and communities across the nation. The version of the virus that people were first exposed to will likely dictate how they respond to new vaccines and variants, according“There are no cookie-cutter answers here,” John Moore, PhD, a professor of microbiology and immunology at Weill Cornell Medicine, told the newspaper.
Known as “original antigenic sin” in the scientific community, the concept means that first exposure can direct later responses in the body. People’s immune systems are responding in different ways, which has prompted questions about reinfections, updated booster shots, and protection against new variants.based on the original coronavirus strain continue to protect people against severe disease and hospitalization, the newspaper reported.
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