The reactogenicity and impact of coronavirus disease 2019 (COVID-19) vaccines on pregnancy outcomes.
By Dr. Chinta SidharthanReviewed by Lily Ramsey, LLMJun 18 2024 In a recent study published in BMJ Global Health , a team of researchers conducted a systematic review of major databases and a meta-analysis to examine the reactogenicity and impact of coronavirus disease 2019 vaccines on pregnancy outcomes related to severe acute respiratory syndrome coronavirus 2 infections among women in perinatal or pregnancy stages.
While the COVID-19 vaccine has been the single most effective intervention in limiting the spread of the pandemic and decreasing the severity of infections, a majority of the phase III trials for various COVID-19 vaccines did not include pregnant women, leading to a lack of clarity about the efficacy and safety of COVID-19 vaccination among pregnant women.
About the study In the present study, the researchers conducted a systematic review to comprehensively assess the impact of any COVID-19 vaccine on outcomes related to SARS-CoV-2 infections, reactogenicity, or maternal and infant health when administered to women before or during pregnancy. The study population in these studies consisted of pregnant women exhibiting symptoms similar to COVID-19, and the examined outcomes included SARS-CoV-2 infections in mothers and outcomes related to maternal hospital admissions. The outcomes also included COVID-19-like illness in the neonates.
Infection-related outcomes extracted from the studies included the number of vaccinated or unvaccinated women; maternal SARS-CoV-2 diagnosed before pregnancy; hospital admission, severe COVID-19, or death due to COVID-19 among mothers; and outcomes in offspring such as infection within six months of birth.
The commonly reported side effect after vaccination was pain at the injection site. The meta-analysis reported that pregnant women who had completed the COVID-19 vaccination regimen had 61% lower odds of getting SARS-CoV-2 infection during their pregnancy and 94% lower probability of requiring hospital admission due to COVID-19.
Covid-19 CLARITY Coronavirus Diabetes Efficacy Global Health Hospital Mortality Pandemic Pregnancy Research Respiratory SARS SARS-Cov-2 Severe Acute Respiratory Severe Acute Respiratory Syndrome Syndrome Vaccine
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Half expect cashless society 'in lifetime', 15% never carry moneyThe amount of money taken out of cashpoints has dropped by a third since 2019
Read more »
Numbers going to church increase, but still below 2019 levelOverall average weekly attendance at Church of England services rose by almost 5% last year
Read more »
Ken Clarke has ‘questions to address’ over infected blood scandalHe was an MP for Rushcliffe between 1970 and 2019
Read more »
General election date confirmed by Rishi Sunak in announcementThe general election will be the first since Boris Johnson's victory in 2019
Read more »
Portrush Air Show set for take off after five-year absenceThe last Portrush event was staged in 2019, before being cancelled due to mounting costs.
Read more »
Why China, Japan, and South Korea Are Holding Their First Trilateral Summit Since 2019The trilateral summits have been on hold since 2019 due to COVID and China’s anger at Japan and South Korea moving closer to the U.S. in recent years.
Read more »