Sky's science and tech editor aTomClarke meets researchers who are using genetic insights from the pandemic to develop new drugs to tackle severe lung inflammation. Read more here:
"In infectious disease and intensive care medicine, to my knowledge, this is the first time that we've been able to go from a genetic discovery straight to a drug," Prof Baillie tells me.which has identified more than 16 genetic changes that underpin the severe lung inflammation that killed many of those who died from COVID-19.
A new Pandemic Science Hub at the University brings the disciplines they used to make their initial drug breakthrough under one roof: human genetics to identify new drug targets based on genetic signals found in critically ill patients; a drug manufacturing facility to make experimental drugs based on those targets, and a technology team to design better ways of screening those drugs in patients.
For that reason, even the most promising drugs identified using a patient's genetics, may not behave how they expect once they reach their intended target deep in the lung tissue.Prof Baillie and his team have been given £15m to develop new drugs to tackle deadly illnesses
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