Coronavirus updates: Hydroxychloroquine given to 1,300 US veterans with COVID-19

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Coronavirus updates: Hydroxychloroquine given to 1,300 US veterans with COVID-19
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There are more than 152,000 positive cases across New Jersey, which has slowly started to reopen. Gov. Murphy announced that gatherings from 10 to 25 people will now be allowed and recreational campgrounds can reopen.

12:46 p.m.: UK announces new quarantine measures for travelers from June 8 Travelers entering the United Kingdom will have to quarantine for 14 days beginning June 8, the government announced.U.K. nationals will also be required to quarantine.

Spot checks could be conducted for those who enter on or after June 8 to enforce the new rule, and anyone who breaks quarantine will be issued a 1,000 pound fine.The death toll in New Jersey is approaching 11,000, Gov. Phil Murphy said.There are more than 152,000 positive cases across the Garden State, which has slowly started to reopen. Murphy announced that gatherings from 10 to 25 people will now be allowed and recreational campgrounds can reopen. Any organized gatherings, however, must have clear markings to maintain social distancing and any participants are strongly encouraged to wear face coverings. In an aerial view from a drone, attendees watch the movie "The Goonies" at a pop-up drive-in theatre built in the parking lot at the Broadway Commons on May 21, 2020 in Hicksville, N.Y. In an aerial view from a drone, attendees watch the movie "The Goonies" at a pop-up drive-in theatre built in the parking lot at the Broadway Commons on May 21, 2020 in Hicksville, N.Y.Officials in Miami-Dade County, including Mayor Carlos A. Gimenez, said they are aiming to reopen the beaches on June 1. City managers will be meeting with county staff and medical experts over the weekend to determine rules that would be in place for a"safe and secure reopening," according to a statement from the county.11:47 a.m.: Death toll to exceed 110,000 by June 13: CDC Although COVID-19 deaths in the United States are likely to slow down, the Centers for Disease Control and Prevention anticipates they will still exceed 110,000 by June 13. The CDC says states with low numbers of deaths reported to date will most likely not see a rapid rise in the coming weeks, while states with high numbers to date are likely to see increases"at varying rates." An ABC News analysis predicts that the number of fatalities could reach 100,000 in the next few days.The official death in the U.S. is 94,729, according to data compiled by Johns Hopkins University.Long Island and mid-Hudson could begin reopening by next week, Gov. Andrew Cuomo said.Throughout the state, the number of hospitalizations and new cases per day were down. In an aerial view from a drone, attendees watch the movie "The Goonies" at a pop-up drive-in theatre built in the parking lot at the Broadway Commons on May 21, 2020 in Hicksville, N.Y. In an aerial view from a drone, attendees watch the movie "The Goonies" at a pop-up drive-in theatre built in the parking lot at the Broadway Commons on May 21, 2020 in Hicksville, N.Y.Cuomo called the daily death toll"stubborn." An additional 109 people died in the last 24 hours, according to the governor. He announced that a new pilot program was launched, with 52 independent hospitals that would allow the state to conduct 7,000 more tests per week. This is in addition to the 700 plus locations where New Yorkers can already get tested.With Memorial Day weekend coming up, he also pleaded with residents to stay vigilant if they go out to parks or beaches.The U.S. Department of Veterans Affairs has administered hydroxychloroquine to some 1,300 American veterans who tested positive for the novel coronavirus, Senate Minority Leader Chuck Schumer said Friday. In response to Schumer's questions in a letter sent earlier this month, U.S. Secretary of Veterans Affairs Robert Wilkie wrote that around 13% of the more than 10,000 veterans currently being treated for COVID-19 at VA medical facilities have been given the antimalarial drug so far. That includes residents of the Long Island State Veterans Home in Stony Brook, New York, which has one of the highest number of reported coronavirus-related deaths of any nursing home on Long Island.The US Department of Veterans Affairs building is seen in Washington, D.C., on July 22, 2019.Wilkie wrote in his letter, which the New York Democrat released to the press Friday, that more veterans are set to receive hydroxychloroquine as part of previously unannounced clinical trials. "What the information presented to me by the VA shows is that the original VA study on hydroxychloroquine that everyone was concerned over is really just the beginning," Schumer said in a statement. “What I am able to say today is that more than 1,000 vets have been given hydroxychloroquine, a clinical trial is set to launch in California and other states that could begin as soon as next week. Why did we not know this until now? What happened to the 1,300 vets who took this drug so far and where will the next trials take place. We need these answers and we need them now." 9:22 a.m.: Study shows coronavirus patients treated with Trump-touted antimalarial drug at higher risk of death A study of more than 96,000 coronavirus patients in hospitals around the world found that those who were treated with chloroquine or its analogue hydroxychloroquine had a considerably higher risk of death than those who did not receive the antimalarial drugs.Friday in the Lancet medical journal, show that COVID-19 patients who received these medications, either alone or in combination with macrolide antibiotic, were also more likely to develop serious cardiac arrhythmias, which cause the lower chamber of the heart to beat rapidly and irregularly. "This is the first large-scale study to find statistically robust evidence that treatment with chloroquine or hydroxychloroquine does not benefit patients with COVID-19," Dr. Mandeep Mehra, lead author of the study and executive director of the Brigham and Women’s Hospital Center for Advanced Heart Disease in Boston, said in a statement."Instead, our findings suggest it may be associated with an increased risk of serious heart problems and increased risk of death. Randomized clinical trials are essential to confirm any harms or benefits associated with these agents. In the meantime, we suggest these drugs should not be used as treatments for COVID-19 outside of clinical trials." A pharmacy tech pours out pills of Hydroxychloroquine at Rock Canyon Pharmacy in Provo, Utah, on May 20, 2020. A pharmacy tech pours out pills of Hydroxychloroquine at Rock Canyon Pharmacy in Provo, Utah, on May 20, 2020.A team of researchers analyzed data from 96,032 patients hospitalized between Dec. 20, 2019, and April 14 who had tested positive for the novel coronavirus at 671 hospitals across six of the world's seven continents -- North America, Europe, Asia, Africa, South America and Australia. All of the patients included in the study had either been discharged or had died by April 21. The team assessed the outcomes of 1,868 patients who were treated with chloroquine alone, 3,016 patients treated with just hydroxychloroquine, 3,783 patients treated with chloroquine in combination with a macrolide and 6,221 patients treated with hydroxychloroquine in combination with a macrolide. Patients from these four groups were compared with the remaining control group of 81,144 patients. At the end of the study, around one in 11 patients in the control group had died in the hospital. All four treatment regimens were associated with a higher risk of dying in the hospital. Of those treated with just chloroquine or hydroxychloroquine, around one in six patients had died. When the drugs were used in combination with a macrolide, the death rate increased to more than one in five for chloroquine and almost one in four for hydroxychloroquine. "Several countries have advocated use of chloroquine and hydroxychloroquine, either alone or in combination, as potential treatments for COVID-19," Dr. Frank Ruschitzka, who co-authored the study and is the director of the Heart Center at University Hospital Zurich, said in a statement."Justification for repurposing these medicines in this way is based on a small number of anecdotal experiences that suggest they may have beneficial effects for people infected with the SARS-CoV-2 virus. However, previous small-scale studies have failed to identify robust evidence of a benefit and larger, randomized controlled trials are not yet completed. However, we now know from our study that the chance that these medications improve outcomes in COVID-19 is quite low." President Donald Trump arrives on the South Lawn of the White House after returning from a trip to Michigan, May 21, 2020, in Washington. President Donald Trump arrives on the South Lawn of the White House after returning from a trip to Michigan, May 21, 2020, in Washington.Chloroquine is an antimalarial drug and its analogue, hydroxychloroquine, is used to treat autoimmune diseases, including arthritis and lupus. Both medications have been deemed generally safe when used for those specific conditions, and the study's findings do not imply patients should stop taking those drugs if already prescribed. The two drugs have also been shown in laboratory conditions to have antiviral properties as well as immunomodulatory effects, which is why they are seen as potential treatments for COVID-19.

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