Coronavirus: SA to start enrolling patients in landmark Covid-19 trial By Adele Baleta for Spotlight
Enrolment of Covid-19 positive patients at 14 hospitals countrywide begins in the next two weeks and is being coordinated by Wits University researchers, Professors Helen Rees and Jeremy Nel.
The South African Solidarity research team is led by senior academics and clinicians from eight medical schools. The leading hospitals are: After the physician states which drugs are available at his or her hospital, the trial randomisation centre at the WHO will then inform the doctor as to which of five treatment groups the patient is randomly allocated; one of the four treatment arms or the usual standard of care for Covid-19 in the country.
Each trial participant has to sign an informed consent form that is scanned and sent to WHO electronically. Rees said the consent forms, only three pages, is simple, translated into all local languages, and the patients would sign it themselves. However, evidence from individual cases doesn’t prove a drug is safe and effective, which is why the WHO initiated the Solidarity Trial. The drug is both potent and expensive. Rees said that in the South African setting, we are constantly looking for cheaper products and if Remdesivir is proven effective for Covid-19, we would look for cost effective alternatives.are very closely related, and are used to treat malaria and rheumatology conditions respectively.
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