Asymptomatic people had "weaker" immune responses to COVID-19, and 40% of them had no detectable antibodies after a couple of months.
People who develop coronavirus-fighting antibodies might not keep them very long, especially if they didn't have symptoms.
The study was meant to address two key questions that will inform how the world responds to the pandemic in the coming months: Do most people develop immunity after infection? And how long does that protection last?For many of the participants in the study, however, antibodies only seemed to last a couple months. About eight weeks after recovery, antibodies dropped to undetectable levels in 40% of the asymptomatic people and in 13% of those who had symptoms.
The Wanzhou study's sample size was small, though, and antibody tests can be unreliable on a person-to-person basis.The Wanzhou researchers tested for two types of antibodies: immunoglobulin G and immunoglobulin M . Seven people from the new study's asymptomatic group and six from the symptomatic group did not test positive for IgG antibodies three to four weeks after they were exposed to the virus. Even more participants did not have detectable levels of IgM.
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