Commonly Used Meds Tied to Lower Risk for Brain Aneurysm Rupture

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Commonly Used Meds Tied to Lower Risk for Brain Aneurysm Rupture
Cerebral AneurysmBrain AneurysmHemorrhage
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Commonly prescribed drugs are associated with lower risk for aneurysmal subarachnoid hemorrhage. Conversely, four other meds were tied to an increased risk for the condition.

Five commonly prescribed drugs may be associated with a lower risk for aneurysmal subarachnoid hemorrhage , a drug-wide association study suggested.

"The motivation for this study was the fact that we can currently prevent bleeding from intracranial aneurysms only by invasive treatment of those aneurysms with inherent complication risks," study investigator Ynte Ruigrok, MD, PhD, associate professor of neurology and neurosurgery, University Medical Center Utrecht, Utrecht, the Netherlands, told."Drugs to reduce or eliminate this risk are not yet available. This study is a first step in identifying such drugs.

"Hypertension is a major risk factor for occurrence and bleeding from aneurysms. If there is indeed a specific blood pressure-lowering drug that not only has a blood pressure-lowering effect but also has additional protection against aSAH, then perhaps that drug should become the drug of choice in aneurysm patients in the future," he said.

The study's second surprise was the antidiabetic drug metformin and cholesterol-lowering drug simvastatin were also associated with reduced aSAH risk, Ruigrok noted.

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