Some environmental phenols are known to have cardiac toxicities. Now, a new study is revealing their adverse impact on the heart's electrical properties.
Some environmental phenols are known to have cardiac toxicities. Now, a new study is revealing their adverse impact on the heart's electrical properties.
Researchers used data from the Fernald Community Cohort, which includes nearly 10,000 people who lived near the former U.S. Department of Energy uranium processing site at Fernald, outside Cincinnati, and participated in the Fernald Medical Monitoring Program between 1990 and 2008. One goal of the study was to identify any changes in EKG parameters associated with environmental phenol exposure.
Researchers found higher exposure to BPA, BPF and BPA+F in women is associated with a longer PR interval, a delay in the time it takes for electrical signals to move from the atria at the top of the heart to the ventricles. "These were not dramatic changes that we observed, but moderate changes to cardiac electrical activity," he said."However, they were particularly pronounced in certain subpopulations."
Other contributors in this study included Susan Pinney, PhD, FACE, professor of epidemiology in the Department of Environmental and Public Health Sciences; Jack Rubinstein, MD, FACC, professor of clinical cardiology in the Department of Internal Medicine; and Changchun Xie, PhD, professor in the Department of Biostatistics, Health Informatics and Data Sciences.
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