A new study has identified a unique brain network that links varied patterns of brain atrophy, or shrinkage, associated with schizophrenia.
Research synthesizes results from 90 published neuroimaging studies to uncover a unique schizophrenia brain network that could inform treatment plans
"One explanation could be that everyone's actually looking at the same thing from a different vantage point. If multiple people try to feel different parts of an elephant with their eyes closed, they're going to describe different things," said senior author Shan H. Siddiqi, MD, a psychiatrist at the Brigham's Center for Brain Circuit Therapeutics."Our approach with this study was to try to reconstruct the elephant.
The researchers found that the network was similar across patients with contrasting symptoms or at different stages of schizophrenia and did not significantly change with antipsychotic treatments. Patients at high risk of developing schizophrenia shared similarities in atrophy, but there was a unique connectivity pattern in patients who had progressed to clinical disease.
Nervous System Brain Tumor Birth Defects Schizophrenia Mental Health Disorders And Syndromes Brain-Computer Interfaces
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