There are reports of COVID-19 patients who tested negative when they were discharged from hospital, before testing positive again, says an observer.
When we encounter an infection for the first time, our body needs to respond quickly to the threat. So within hours, it activates our innate immune system. This system is quick-acting but isn’t targeted to the specific threat.
Scientist Linqi Zhang shows a tube with a solution containing COVID-19 antibodies in his lab in Beijing. So a positive antibody blood test to COVID-19 doesn’t confirm if someone is immune to COVID-19 or not. It only tells us if a person has ever been exposed to COVID-19 – and even that depends on how sensitive and specific the antibody test is.There are reports from different countries of people hospitalised with COVID-19 who tested negative when they were discharged, before testing positive again.
A study from 1990 found infection with human coronavirus 229E generated protective immunity from that particular virus. There is debate if other coronaviruses provide cross-immunity against COVID-19. Cross-immunity is where immunity against one infection provides protection from another infection.
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