Columbia Researchers Reveal How Our Brains Fuel Curiosity

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Columbia Researchers Reveal How Our Brains Fuel Curiosity
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Researchers at Columbia have linked curiosity to brain activity in areas that process uncertainty and confidence. This discovery, which explains the neural mechanisms behind curiosity, could also inform treatments for mental health issues like depression.

A research team based at Columbia’s Zuckerman Institute has for the first time witnessed what is happening in the human brain when feelings of curiosity like this arise. In a study published in the Journal of Neuroscience, the scientists revealed brain areas that appear to assess the degree of uncertainty in visually ambiguous situations, giving rise to subjective feelings of curiosity.

Human brain-scan images show regions toward the back and front that are active for a person who is feeling curious. Credit: Gottlieb Lab/Columbia’s Zuckerman Institute The researchers used these patterns to develop a measure, which they dubbed “OTC uncertainty,” of how uncertain this cortical area was about the category of a distorted texform. They showed that, when subjects were less curious about a texform, their OTC activity corresponded to only one barcode, as if it clearly identified whether the image belonged to the animate or the inanimate category.

Importantly, said Dr. Gottlieb, vmPFC activity seemed to provide a neurological bridge between the subjective feeling of curiosity and the OTC certainty measure. It’s as though this region read out the uncertainty encoded by the distributed activity pattern in the OTC and helped a person decide if they needed to be curious about the texform.

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