Coffee's 'Sweet Spot': Daily Consumption and Cardiometabolic Risk

Cardiometabolic Risk News

Coffee's 'Sweet Spot': Daily Consumption and Cardiometabolic Risk
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How many daily cups of joe can be beneficial to health?

Associate Professor, Department of Medicine, Yale School of Medicine; Director, Clinical and Translational Research Accelerator, Yale School of Medicine, New Haven, Connecticut, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine.

The JCEM study leveraged the impressive UK Biobank dataset to figure this out. The Biobank recruited more than half a million people from the UK between 2006 and 2010 and collected a wealth of data from each of them: surveys, blood samples, biometrics, medical imaging — the works. And then they followed what would happen to those people medically over time. It's a pretty amazing resource.

These are the results of the fully adjusted model. Compared with nonconsumers, you can see that people in the higher range of coffee, tea, or just caffeine intake have almost a 40% reduction in cardiovascular disease in follow-up. In this study, researchers measured 168 individual metabolites. Eighty of them, nearly half, were significantly altered in people who drank more coffee. But here's how to interpret it. The inner ring shows you how certain metabolites are associated with cardiovascular disease. The outer rings show you how those metabolites are associated with coffee, tea, or caffeine. The interesting part is that the sections of the ring are very different colors.

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