CHOP researchers are on a team getting up to $25 million to fight childhood cancers

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CHOP researchers are on a team getting up to $25 million to fight childhood cancers
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CHOP physician Yael Mossé is the co-leader of the team tackling neuroblastoma, medulloblastoma, and other childhood cancers described as 'undruggable.'

CHOP physician Yael Mossé is the co-leader of the team tackling neuroblastoma, medulloblastoma, and other childhood cancers described as"undruggable."

Instead, the team is developing drugs to degrade rogue proteins that are unique to these five cancers and not found in surrounding healthy cells.The cancers the group is targeting include: neuroblastoma , Ewing sarcoma , fibrolamellar hepatocellular carcinoma , medulloblastoma , and rhabdomyosarcoma .

“Each of the projects that applied for this funding were worthy, so we do not take this award lightly,” she said.In an interview, Wolpaw said the group will develop drugs that enhance the body’s ability to identify and dispose of cancerous proteins that feed the growth of tumors.

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