Lebrikizumab is a monoclonal antibody that binds to cytokine IL-13, which has been implicated in driving the type-2 inflammatory loop in the skin, leading to skin barrier dysfunction.
The Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended marketing authorization of lebrikizumab for the treatment of adult and adolescent patients with moderate to severeLebrikizumab is an investigational, monoclonal antibody that binds to cytokine interleukin
-13, which has been implicated in driving the type-2 inflammatory loop in the skin, leading to skin barrier dysfunction, itch, skin thickening, and infection. The biologic is being developed by Almirall and is designed to be administered once per month. Lebrikizumab is not yet available in the United States.
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