Study in China finds that PAPPA protein when triggered by signaling protein–sirtuins drives rapid aging in humans.
Scientists have recently discovered that an increased level of a protein known as PAPPA–pregnancy-associated plasma protein-A, prompted further by a family of signaling proteins–sirtuins are a “common driver” of
Additionally, the study also reported that deficiency in any of the seven sirtuins led to accelerated cellular aging. The study shared new insights into the process of aging, particularly highlighting the role of PAPPA. Although first identified as one of four proteins found at high levels in the plasma of pregnant women, PAPPA’s function was unknown for decades, reported
Scientists have been examining sirtuins with a focus on studying if calorie restriction slows down the aging process or not.
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