Caspase-7 activates ASM to repair gasdermin and perforin pores - Nature

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Caspase-7 activates ASM to repair gasdermin and perforin pores - Nature
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Scientists reveal function of celldeath enzyme capsase-7 nature

We thank R. Flavell, V. Dixit, R. Vance and M. Deshmukh for sharing mice directly or through The Jackson Laboratory. This work was supported by the following NIH grants: AI097518, AI133236, AI139304, AI119073, AI136920 AI097518-02S1 , R56AI110682 and R01AI074862 , R01AI050072 and P30CA016086 . We also thank T. Abele, F. Lakhani, M. Artunduaga, M. DePrizio, S. Pereles, A. Vaidyanathan, R. Eplett, M. Mann, S. Redecke and L. Scarpelli for mouse colony upkeep.

Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USADepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA Vivien I. Maltez, Manira Rayamajhi, Alan L. Tubbs, Joseph E. Mitchell, Carissa K. Harvest, Lupeng Li, Benjamin D. McGlaughon, Nathaniel J. Moorman & Jason K. WhitmireJoseph E. Mitchell & Jason K. Whitmire

Department of Medicine, Division of Nephrology and the Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA

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