Persephone Biosciences is working a technology platform for products that target microbes linked to a healthy immune system.
San Diego’s Persephone Biosciences, a startup working on cancer therapies and precision probiotics based on the gut microbiome, has landed $15 million in early stage seed investment.
“I think of the microbiome as the gatekeeper of our immune system,” said Stephanie Culler, chief executive and co-founder of Persephone. “It is essentially the collection of microbes that line our gastrointestinal tract and serve to promote normal immune function to prevent disease. Eighty percent of our immune cells are in our gut, so the type of microbes that we have are important to having robust immune health.
“We are really looking to have a comprehensive data-set that understands the function of the microbiome in these oncology patients to develop the next generation of microbiome therapies,” she said. “The issue here, and it is becoming a multi-generational worldwide problem, is many babies today are being born without the right microbes to train their immune systems to help prevent disease,” said Culler. “And that is one of the contributors as to why we are seeing such a large increase in food allergies and other issues.”
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