An article published in BMCBioInformatics presents CAGECAT: a rapid and user-friendly platform to mitigate difficulties in comparative analysis of whole gene clusters.
Example output of
provides interoperation between results and the available modules. Selections of output from the search module can be directly used as input for downstream analysis or to recompute a search using different parameters . Notably, when genomic regions from the search module are used for analysis in the visualisation module, it will include all genes present within each genomic region that were not specified in the search query.Post-job execution screen for selective downstream analysis.
: finding homologous gene clusters using a query cluster and the cblaster search module, and a visualisation of gene clusters using a set of query clusters and the clinker module.
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DNA inherited from Neanderthals may impact human nose shape, study findsResearchers from University College London (UCL) say the gene may have come from natural selection as ancient humans adapted from colder climates after leaving Africa.
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DNA inherited from Neanderthals may impact human nose shape, study findsResearchers from University College London (UCL) say the gene may have come from natural selection as ancient humans adapted from colder climates after leaving Africa.
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The effect of COVID-19 on women’s experiences of pregnancy, birth and postpartum in Indonesia: a rapid online survey - BMC Pregnancy and ChildbirthBackground The interrelationship of psychological and social factors in the current COVID-19 pandemic has been highlighted in research mainly focused on the global north. The impact of lockdowns can exacerbate psychological distress and affect access to services. Less is known about the psychosocial impact on women in the context of lower-middle income countries (LMICs); the aim of this study was to capture the impact of COVID-19 on women’s experiences of pregnancy, birth and postpartum in Indonesia. Methods We conducted a rapid cross-sectional online survey of women across all 34 provinces in Indonesia to capture participants’ experiences. Data were collected between 10th July to 9th August 2020 including demographics, effects on general and mental health and impact on service use. Descriptive statistics and thematic analysis were used to analyse responses, including those women who self-identified with a pre-existing mental health problem. Results Responses were obtained from 1137 women, this included pregnant women (n = 842) and postpartum women (n = 295). The majority of women (97%) had accessed antenatal care during their pregnancy, but 84% of women reporting feeling fearful and anxious about attending visits, resulting in some women not attending or changing provider. A small number (13%) were denied the presence of a birth companion, with 28% of women reporting that their babies had been removed at birth due to protocols or baby’s health. Feeling anxious was a common experience among women (62%) during their pregnancy, birth or postnatal period, with a small number (9%) feeling depressed. Lockdown measures led to tensions within personal and family relationships. Conclusions Women in Indonesia reported that the pandemic added an increased burden in pregnancy, birth and post-partum period: physically, psychologically, spiritually and financially. Maternity services were disrupted and health insurance cover lacked responsiveness, which either directly or indire
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Missing hillwalker John Gardiner found safe and wellA search was launched for John Gardiner near Blair Atholl after he was reported missing overnight.
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Sexual violence against women remains problematic and highly prevalent around the world - BMC Women's HealthBackground Sexual violence is far more prevalent in most societies than is usually suspected in daily life. However, no study has systematically summarized the global prevalence rate and the major outcomes of sexual violence against women. Methods We directed a wide-raging search in the PubMed, Embase, and Web of Science, catalogs since the beginning to December 2022 for relevant reports about the incidence of sexual fighting touching females. The occurrence frequency was assessed with a random-effects model. The heterogeneity was estimated with I 2 values. Differences by research features were assessed over subgroup evaluation and meta-regression. Results A total of 32 cross-sectional studies were included (a total of 19,125 participants). The pooled sexual violence rate was 0.29 (95% CI = 0.25–0.34). Subgroup analyses found that there was a higher rate of sexual violence against women in 2010–2019 period (0.33, 95% CI = 0.27–0.37), developing countries (0.32, 95% CI = 0.28–0.37), and interview (0.39, 95% CI = 0.29–0.49). The analysis found that more than half of women (0.56, 95% CI = 0.37–0.75) had post-traumatic stress disorder (PTSD) after experiencing sexual violence, and only a third of women considered seeking support (0.34, 95% CI = 0.13–0.55). Conclusions Nearly one out of every three (29%) women around the world has been a victim of sexual violence in their life. This current study investigated the status and characteristics of sexual violence against women, which could provide an important reference for police and emergency health services management.
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Dawn of the drone wars? How Ukraine conflict has set stage for new military capabilitiesThe Ukraine war has seen drones go from next frontier of parcel delivery to cutting edge of warfare technology, with the rapid development of AI set to accelerate things even faster.
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