Meghan Holohan is a digital health reporter for TODAY.com and covers patient-centered stories, women’s health, disability and rare diseases.
Comedian Wanda Sykes, 60, understands the importance of early detection for breast cancer. In 2011, she was diagnosed with ductal carcinoma in situ, an early, curable form of breast cancer in the lining of milk ducts in the breast, according to the American Cancer Society. In a Super Bowl 2025 ad for Novartis, Sykes stresses how early detection transformed her life. “Let’s start paying attention to breasts when it matters the most,” she says.
It recommends women with average risk of breast cancer undergo regular mammograms because they’re the best way of finding early breast cancers starting at age 40. After undergoing a breast reduction, Sykes learned she had ductal carcinoma in situ, according to People. Her treatment plan included a double mastectomy. “To me, it was like, ‘They’re just boobs,’” she told People. “Do you want your boobs or your life? I went with life.
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