Scientists have shed new light on the role of GABA, a key signaling molecule in the brain. Researchers have delved into how GABA's levels in the brain are regulated and its broader impacts on cognitive function.
, scientists have shed new light on the role of GABA, a key signaling molecule in the brain. Researchers from the Center for Cognition and Sociality within the Institute for Basic Science , led by Director C. Justin LEE and Young Scientist Fellow KOH Wuhyun, and Yonsei University team, led by Professor CHEONG Eunji and Postdoctoral Researcher KWAK Hankyul, have delved into how GABA's levels in the brain are regulated and its broader impacts on cognitive function.
Since 2010, Director Lee has been investigating the cognitive function of astrocytes, a type of brain cell involved in the synthesis, release, and clearance of GABA. His team even identified potential treatments for diseases related to aberrant GABA synthesis, such as dementia, and are pioneering the development of these therapies.
Second, Mechanism of Tonic GABA Current Inhibition: There was a misconception in the literature that inhibition of tonic GABA currents was mediated by hyperpolarization, but this type of inhibition occurs with a specific form of resistance reduction known as shunt inhibition.
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