Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder? - Journal of Translational Medicine

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Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder? - Journal of Translational Medicine
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Brain fog after COVID-19 shows similar symptomatology and cognitive patterns with Chronic Fatigue Syndrome (CFS), with greater impairment in CFS, reports a study published in the Journal of Translational Medicine.

The objective of this study is to analyze the differences and similarities between CFS/ME and post-COVID-19 condition, focusing especially on the neuropsychological characteristics of both.Patients aged 18–85 years with a sufficient understanding and communication skills, with post-COVID-19 condition and with ME/CFS were recruited from those attending the Neurology Department at Cruces University Hospital.

For patients to be diagnosed with post-COVID-19 condition, any of the following symptoms had to be present at least 3 months after the infection and persisting for at least 2 months []: physical fatigue, mental fatigue, palpitations, sensory symptoms and/or dysautonomic symptoms.

The neuropsychological and neuropsychiatric evaluation was performed in a single day, lasting approximately one hour and a half. To avoid cognitive fatigue, the DSQ was completed by the patients at home.Statistical analyses were carried out using IBM SPSS Statistics for Windows, version 23.0 . For the cognitive variables’ raw data that fulfilled the normality assumption, the Student's t test was carried out to compare the means between groups. In the case of the tests that did not meet this assumption, the U Mann–Whitney test was performed. The raw data of the cognitive test was also transformed into Z scores for each group to create cognitive composites.

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