UCLA study is the most comprehensive effort ever to study how autism affects the brain at the molecular level. Brain changes in autism are comprehensive throughout the cerebral cortex, not only confined to particular regions traditionally considered to affect language and social behavior. These a
According to new research, brain changes in autism are comprehensive throughout the cerebral cortex rather than just particular areas thought to affect social behavior and language
Brain changes in autism are comprehensive throughout the cerebral cortex, not only confined to particular regions traditionally considered to affect language and social behavior. These are the findings of a new study, led by the University of California, Los Angeles , which substantially refines scientists’ understanding of how autism spectrum disorder progresses at the molecular level., the study represents a comprehensive effort to characterize ASD at the molecular level.
“This work represents the culmination of more than a decade of work of many lab members, which was necessary to perform such a comprehensive analysis of the autism brain,” said study author Dr. Daniel Geschwind, the Gordon and Virginia MacDonald Distinguished Professor of Human Genetics, Neurology and Psychiatry at UCLA.
While each profiled cortical region showed changes, the largest drop off in gene levels were in the visual cortex and the parietal cortex, which processes information like touch, pain and temperature. The researchers said this may reflect the sensory hypersensitivity that is frequently reported in people with ASD.
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