Increased thiazide doses were associated with a greater decrease in urine calcium and kidney stone events over a 4-year period in adults who had kidney stones.
Higher thiazide doses are linked to greater reductions in urine calcium levels, which correlate with fewer symptomatic kidney stone events. This association suggests that adjusting thiazide dosage could be crucial in kidney stone prevention.
Medium Changes in calcium levels in response to low, medium, and high thiazide dosages were evaluated. These changes were correlated with the incidence of symptomatic stone events, identified by emergency department visits, hospitalizations, or surgeries for stones within 6-48 months after the initial prescription fill.Higher thiazide doses were associated with greater reductions in urine calcium levels, with a low dose resulting in an 18.9% reduction, a medium dose in a 25.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Nephrolithiasis Renal Calculus Renal Calculi Kidneys Calcium Osteoarthritis Generalized Osteoarthritis OA - Osteoarthritis DJD - Degenerative Joint Disease Degenerative Arthritis Generalised Osteoarthritis Osteoarthritis (OA) Adverse Effects Side Effects Artificial Intelligence Deep Learning AI NPL Machine Learning ML Natural Language Processing
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