Blood Flow Imbalance May Explain Alzheimer's Neurodegeneration

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Blood Flow Imbalance May Explain Alzheimer's Neurodegeneration
ALZHEIMER's DISEASENEURODEGENERATIONNEUROVASCULAR UNIT
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A new study suggests that a mismatch between blood flow and neuron activity in the brain could be a key factor in the development of Alzheimer's disease. Researchers found that this discrepancy could be used as a simple and inexpensive diagnostic tool for the disease, and may also offer a new target for treatment.

A mismatch between blood flow and neuron activity in the brain may underlie the harmful neurodegeneration seen in Alzheimer's disease.This is the conclusion of an international team of researchers who say that the discrepancy could be exploited as a simple way to diagnose the progressive neurological disorder—and may afford a new target in efforts to treat the disease.

At the same time, an electrocardiogram monitored heart rate, while a belt around each subject's chest recorded breathing patterns.This suite of instruments allowed the team to capture the test subjects' physiological rhythms—and determine how in time they all were.As the researchers explain, the synchronization of all these rhythms is essential for the efficient functioning of the brain.

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