Birth weight and maternal BMI modify the relationship between obesity and mortality rate Birth Weight Mortality Obesity AnnalsOfEpi UofAlabama IndianaUniv Atarabio
Study: Birth Weight Moderates the Association Between Obesity and Mortality Rate. Image Credit: zlikovec / Shutterstock
To illustrate, "a mismatch between an anticipated environment and the actual environment may adversely affect health and longevity." "These hypotheses [that the association between the BMI of the offspring and the mortality rate varies by birth weight and by maternal BMI] stem from the more general proposition that a mismatch between a propensity to obesity and achieved adult body weight increases the MR associated with being obese." This might help us understand why the prevalence of obesity is increasing while the risk of death from cardiovascular disease is falling, along with the associated risk factors.
The association of the offspring BMI with mortality was stronger in individuals with lower birth weight, as expected. This is explained by the fact that low birth weight predisposes the individual to hoard scarce nutritional resources when they become available in the form of fat. When such an individual is exposed to food in plenty, the adiposity grows to potentially produce overweight or obese people.
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