Get Houston Astros vs San Francisco Giants predictions, picks, and odds for 6-10, plus MLB best bets and same-game parlay analysis.
Jose Altuve is the one Astro we can trust to do some damage against left-handed pitchers. With lefty Kyle Harrison taking the mound for San Francisco, that's where our MLB betting picks are looking.
We have a long track record of success to fall back on and I’m choosing not to ignore it. He has a .323 BA, .887 OPS, and .181 ISO against lefties, both hitting for contact and power better than he does against righties. but still has much to prove. He posted a 4.55 xERA, 5.53 FIP, and 5.01 xFIP across his first seven starts in the MLB as a 21-year-old a year ago. This year’s 4.18 ERA is decent but his 4.69 xERA is a concern yet again.
Harrison has allowed 3+ earned runs in each of his last five starts. The wind is blowing out at nine mph which is standard at Oracle Park, where the youngster has a 4.65 ERA and 1.45 WHIP across 31 IP this season. Harrison pitches to contact and batters have been happy to smash his offerings. Shortstop Jeremy Pena has been effective against lefties, posting a .829 OPS and .309 BA since 2022.
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