AstraZeneca pauses COVID-19 vaccine trial after unexplained illness

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AstraZeneca pauses COVID-19 vaccine trial after unexplained illness
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Holds during clinical trials are not uncommon, but this is thought to be the first time it has happened for a COVID-19 vaccine trial.

AstraZeneca is one of nine companies currently in late-stage Phase 3 trials for their vaccine candidates.The vaccine, called AZD1222, uses a weakened version of a common cold causing adenovirus that has been engineered to code for the spike protein that the novel coronavirus uses to invade cells.

After vaccination, this protein is produced inside the human body, which primes the immune system to attack the coronavirus if the person is later infected. –

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