A study published in Crit_Care finds that early nutrition support in the ICU is significantly associated with increased mortality at day 28. This may challenge the current guidelines and practices, particularly concerning patients at low nutrition risk.
The study was approved by the French Committee for the Protection of Human Subjects in Biomedical Research Paris Ile de France IV Saint-Louis and by the Belgium ethics committee of Erasme Universitary Hospital . The access to health information was approved by the French Data Protection Committee .
]. Participants' confidentiality was strictly observed throughout the study using the anonymous unique serial number for each subject and restricting data only to the investigators. This study was retrospectively registered on November 5th 2015 .Competing interests E.P. received a research grant from Nestle Healthscience, teaching fees from Fresenius Kabi and congress reimbursement from Fresenius Kabi and Nutricia. T. L. received consultant’s fees from Fresenius Kabi.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.: Propensity score balance.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study - BMC MedicineBackground Observational studies have linked childhood obesity with elevated risk of colorectal cancer; however, it is unclear if this association is causal or independent from the effects of obesity in adulthood on colorectal cancer risk. Methods We conducted Mendelian randomization (MR) analyses to investigate potential causal relationships between self-perceived body size (thinner, plumper, or about average) in early life (age 10) and measured body mass index in adulthood (mean age 56.5) with risk of colorectal cancer. The total and independent effects of body size exposures were estimated using univariable and multivariable MR, respectively. Summary data were obtained from a genome-wide association study of 453,169 participants in UK Biobank for body size and from a genome-wide association study meta-analysis of three colorectal cancer consortia of 125,478 participants. Results Genetically predicted early life body size was estimated to increase odds of colorectal cancer (odds ratio [OR] per category change: 1.12, 95% confidence interval [CI]: 0.98–1.27), with stronger results for colon cancer (OR: 1.16, 95% CI: 1.00–1.35), and distal colon cancer (OR: 1.25, 95% CI: 1.04–1.51). After accounting for adult body size using multivariable MR, effect estimates for early life body size were attenuated towards the null for colorectal cancer (OR: 0.97, 95% CI: 0.77–1.22) and colon cancer (OR: 0.97, 95% CI: 0.76–1.25), while the estimate for distal colon cancer was of similar magnitude but more imprecise (OR: 1.27, 95% CI: 0.90–1.77). Genetically predicted adult life body size was estimated to increase odds of colorectal (OR: 1.27, 95% CI: 1.03, 1.57), colon (OR: 1.32, 95% CI: 1.05, 1.67), and proximal colon (OR: 1.57, 95% CI: 1.21, 2.05). Conclusions Our findings suggest that the positive association between early life body size and colorectal cancer risk is likely due to large body size retainment into adulthood.
Read more »
Residents association saved at the last minuteA much-loved residents association was saved at the last minute after fears were raised that it could close for good.
Read more »
Newcastle United midfielder Joelinton charged with drink driving in early hours todayNews on Thursday afternoon - Newcastle United midfielder Joelinton charged with drink driving in early hours today.
Read more »
Glasgow man in court over alleged early-hours murder bid on city centre streetA 34-year-old man was rushed to hospital after the alleged attack on Glassford Street at 1am on Sunday, December 18, 2022.
Read more »
I had the perfect middle name for my baby - she ruined it when she came earlyIT can be more than a little difficult to settle on the perfect name for your baby. Mum Tiffany was inspired by her daughter’s due date when she came up with a middle moniker for her little g…
Read more »
The Apprentice candidate makes shock exit and quits competition early🔴 Spoiler Alert | One the of TheApprentice candidates decided to shockingly leave the competition early during tonight's episode 😱
Read more »