Are the PAD Interventions for Men Safe in Women?

Peripheral Vascular Disease News

Are the PAD Interventions for Men Safe in Women?
Peripheral Artery DiseasePeripheral Arterial DiseasePeripheral Arterial Occlusive Disease
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Women are underrepresented in endovascular therapy trials. A new analysis of REVIVE data delves into the stent and bypass surgical outcomes for women.

, interventionalists have scant clinical evidence on which approach is best for their female patients.

"In patients with symptomatic PAD involving the femoropopliteal segment, endovascular therapy with stent implantation vs bypass surgery was associated with a similar rate of 2-year major adverse limb events and amputation-free survival, but a lower rate of complications and significantly lower lengths of hospitalization, regardless of sex," Serdar Farhan, MD, assistant professor at the Icahn School of Medicine at Mount Sinai in New York City, reported here at the Society for...

The goal, Farhan said, was to evaluate 2-year rates of major adverse limb events and other key outcomes such as amputation-free survival and primary patency. Shorter-term endpoints were 30-day complications related to a composite of bleeding, infection, and death as well as bleeding and infection as singular findings.

"Interestingly, we saw that the composite of bleeding, infections, or death within 30 days is significantly less with endovascular therapy in both sexes," he added, noting that the rate of bleeding in women who had endovascular therapy was one third the rate in those who had bypass surgery, whereas in men, the bleeding rate with endovascular therapy was half that of bypass.

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Peripheral Artery Disease Peripheral Arterial Disease Peripheral Arterial Occlusive Disease Endovascular Techniques Endovascular Surgery Endovascular Therapy Endovascular Repair Endovascular Stent Cardiac Surgeries Cardiac Surgery Surgery Stent Limbs Hemorrhage Bleeding Healthcare And Medical Technology Health And Medical Tech Health And Med Tech

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