An over-the-counter antihistamine that had shown potential for treatment of multiple sclerosis (MS) in animal studies was linked to significant worsening of symptoms in humans, new trial data suggested.
An over-the-counter antihistamine that showed potential for treating multiple sclerosis (MS) in animal studies was found to worsen symptoms in humans, according to new trial data. The antihistamine, clemastine fumarate, was being tested as a potential MS treatment in an ongoing trial led by the National Institute of Allergy and Infectious Diseases. However, after three participants experienced a fivefold increase in disease progression, the trial was halted.
The results suggest that clemastine may not be an effective treatment for MS
Antihistamine Multiple Sclerosis MS Trial Symptoms Treatment
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