A new study has shown that anti-TNF drugs, commonly used to treat Crohn's disease, can significantly reduce the risk of anal fistulas in children diagnosed with the condition. Anal fistulas are tunnels that form between the anus and the skin outside, leading to open sores and increasing the risk of infections and organ damage.
A new study suggests that anti-TNF drugs, commonly used to treat Crohn's disease, significantly reduce the risk of anal fistulas in children diagnosed with the condition. Researchers found that children taking anti-TNF drugs had an 82% lower risk of developing anal fistulas compared to those who didn't. Anal fistulas are tunnels that form between the anus and the skin outside, leading to open sores and increasing the risk of infections and organ damage.
About 70% of children with anal fistulas require surgery, which can be complex and costly. The study, which tracked over 900 children newly diagnosed with Crohn's disease, also showed that the presence of anal ulcers, fissures, or lesions significantly increased the risk of developing fistulas. Anti-TNF drugs, which block the inflammatory substance TNF, appear to be effective in preventing these complications. While anti-TNF drugs are more expensive, the study suggests that their cost-effectiveness outweighs the potential savings from avoiding costly surgeries and complications associated with anal fistulas
Crohn's Disease Anal Fistulas Anti-TNF Drugs Child Health Disease Prevention
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