Science, Space and Technology News 2024
Researchers track the intestinal health of fruit flies with a blue dye, hence the name Smurf. Fruit fly intestines damaged by aging leak the blue dye, this image shows an HRJD-modified fly on the left and an unmodified fly of the same age on the right. Credit: ©2024 Hiroki Nagai CC-BY-NDIn a groundbreaking experiment, Japanese researchers transferred regenerative genes to fruit flies, leading to improved intestinal health and enhanced stem cell activity.
The unbelievably tiny intestine of the adult fruit fly, labeled with fluorescent markers. Credit: ©2024 Yuichiro Nakajima CC-BY-ND “Nagai discovered some novel phenotypes, characteristics that manifest from genes in a given set of conditions,” said Nakajima. “HRJDs promoted greater intestinal stem cell division, whilst also suppressing intestinal cells that were mis-differentiating, or going wrong in aged flies. This is in contrast to the use of antibiotics, for example, which might suppress mis-differentiated intestinal cells, but also suppress intestinal stem cell division.
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