Researchers have developed software to accurately infer continental ancestry from tumor DNA and RNA, potentially helping in early cancer detection and personalized treatments. With over 95% accuracy, the team is now working on more regional specificity and refining their software for individual geno
, the team is now working on more regional specificity and refining their software for individual genomic sequences.
Krasnitz and CSHL Postdoctoral Fellow Pascal Belleau are working to reveal the genealogical connections between cancer and race or ethnicity. They’ve developed Krasnitz’s team trained their software tools using hybrid DNA profiles. They created these profiles from cancerous and unrelated cancer-free genomes of a known background. They then tested the software’s performance against pancreatic, ovarian, breast, and blood cancer specimens from patients with known ancestry. The team found the software matched their hybrid profiles to continental populations with over 95% accuracy.
Krasnitz and Belleau recently joined a colorectal cancer study in collaboration with Northwell Health and SUNY Downstate Medical Center. The study allows them to explore how colorectal cancer mutates genes in different ways depending on specific races or ethnicities. They hope to further refine their software to infer ancestry of not only whole genomes but every individual sequence therein.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Ancient California Fossil Unlocks Secrets of Coffee and Potato Ancestors’ Survival Amid Dinosaur ExtinctionAn ancient 80-million-year-old fossil plant rewrites the history of lamiids, revealing that these flowering plants, including staple crops, evolved earlier than previously believed and suggesting complex rainforests may have existed 80 million years ago. The discovery of an 80-million-year-old fo
Read more »
Dave Filoni Teases New Republic Reveals At Star Wars Celebration’s Ahsoka PanelDay 1 of StarWarsCelebration is just the beginning, and Dave Filoni can't wait for Star Wars fans to find out what New Republic threats and revelations he has in store for the Ahsoka panel:
Read more »
‘The Mandalorian’: All the Star Wars Easter Eggs in Chapter 22All the Easter eggs you missed on this week’s episode of TheMandalorian:
Read more »
Ahsoka Show Trailer Breakdown: 8 Story Reveals & Star Wars SecretsThe first trailer for Star Wars’ upcoming live-action series Ahsoka has been revealed at Star Wars Celebration, brining plenty of big reveals with it.
Read more »
Purported tranche of U.S. and allied military secrets leaked online in major intelligence breachA tranche of what appears to be classified U.S. intelligence material was posted anonymously on the social media platform Discord over the last three months in the latest leak of highly guarded national secrets.
Read more »
US national security documents with Ukraine, China secrets turn up in ‘nightmare’ leakClassified documents that seem to detail US national security secrets related to Ukraine, the Middle East and China have emerged online.
Read more »