An Alabama woman received a pig kidney transplant last month and is free from dialysis for the first time eight years. Towana Looney is the fifth American given a gene-edited pig organ in a quest to make animal-to-human transplants a reality. Importantly, she wasn’t as sick as prior patients who received pig kidneys or hearts.
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Looney is recuperating well after her transplant, which was announced Tuesday. She was discharged from the hospital just 11 days after surgery to continue recovery in a nearby apartment although temporarily readmitted this week while her medications are adjusted. Doctors expect her to return home to Alabama in three months. If the pig kidney were to fail, she could begin dialysis again.
But Looney couldn’t get a match — she had developed antibodies abnormally primed to attack another human kidney. Tests showed she’d reject every kidney donors have offered.and told Locke, at the time a UAB transplant surgeon, she’d like to try one. In April 2023, Locke filed an FDA application seeking an emergency experiment, under rules for people like Looney who are out of options.
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